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Government, corporates and global foundations join hands on PRAGATI to empower 20,000 agri-entrepreneurs
Union Agriculture and Farmers Welfare Minister Shivraj Singh Chouhan recently launched PRAGATI, a nationwide initiative to build 20,000 agri-entrepreneurs and directly benefit 20 lakh smallholder farmers through climate-resilient, regenerative agriculture. Union Minister of Agriculture & Farmers Welfare, Shivraj Singh Chouhan launching the PRAGATI initiative The programme is backed by a coalition of institutions including the PepsiCo Foundation, State...
READ MOREGenespire and SR-TIGET Show Durable Preclinical Efficacy of Liver-Directed Gene Therapy for Methylmalonic Acidemia
Milan, Italy, July 08 -- Genespire, in collaboration with researchers at the San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), has today announced the publication of preclinical data supporting the potential of its liver-directed immune-shielded lentiviral gene therapy approach to treat methylmalonic acidemia (MMA), a severe inherited metabolic disorder. The findings, published in the Journal of Hepatology, show that a single systemic administration of a lentiviral vector encoding the MMUT gene led to sustained improvements in disease features in a validated mouse model of MMA, with effects lasting for the average lifespan of laboratory mice. Since the mice were treated when young, the study supports the durability of the gene therapy through postnatal growth and maturation of the liver. MMA is caused by a deficiency of methylmalonyl-CoA mutase, an enzyme that plays a critical role in the body’s metabolism of food. Its absence results in the accumulation of toxic metabolites that lead to recurrent metabolic crises, growth failure, neurological impairment, and multi-organ damage. In the study, researchers also treated mice with a dose containing an optimized MMUT transgene, thereby improving therapeutic efficacy. In the same mouse model of MMA, this version exhibited a dose-dependent improvement of metabolomic biomarkers, with gene transfer efficiency exceeding 80% of the liver. The study also highlights that genetically corrected cells in the liver may, over time, replace the diseased ones, suggesting that therapeutic efficacy may progressively improve even when starting at lower initial doses. “Together, these findings indicate that Genespire is on a clear path towards the long-term correction of metabolic diseases which impact the liver and other organs,” said Lucia Faccio, CEO of Genespire. “We believe our approach has the potential to translate into human health in the form of a single-administration treatment for patients with MMA, and are committed to continuing our efforts in bringing our lead asset for MMA, GENE202, to the clinic. We would like to extend our gratitude to everyone involved in the research project, especially those at the SR-TIGET.” “We are confident that this study, together with other previous studies from our group at SR-TIGET, provides a comprehensive pre-clinical data package enabling the initiation of clinical testing in pediatric patients affected by MMA” concludes Dr Alessio Cantore, group leader at SR-TIGET and Associate Professor at Vita-Salute San Raffaele University, who supervised and coordinated the study and signed it as senior author....
READ MOREPoshan Tracker Achieves Milestone with 8.93 Crore Beneficiary Coverage
New Delhi, July 8: The Poshan Tracker platform has achieved a major milestone by recording 8.93 crore beneficiaries across the country , strengthening the government’s efforts to improve nutrition monitoring and service delivery. The digital platform has become an important tool for tracking the progress of nutrition programmes and ensuring better coordination among frontline workers, beneficiaries, and implementing agencies. It...
READ MORERobotic Surgery Successfully Removes Rare Tumour in 41-Year-Old Woman
Kochi, July 08: Apollo Adlux Hospital, Angamaly, has achieved a significant medical milestone by successfully removing a posterior mediastinal tumor, a tumor located deep inside the chest cavity close to the spine using advanced robotic surgery . The complex procedure was performed on 41 - year - old Dr Priya Devi, a medical professional, with the tumour being completely removed...
READ MOREMP Expands Digital Healthcare Reach Under Ayushman Bharat Mission
Bhopal, July 8: The Madhya Pradesh Government is working to expand digital healthcare services to the remotest parts of the state under the Ayushman Bharat Digital Mission (ABDM) , with the aim of improving access to quality and affordable healthcare through technology. The initiative focuses on strengthening digital health infrastructure and connecting patients, healthcare institutions, and service providers through an...
READ MOREMonsoon Raises Risk of Leptospirosis and Water-Borne Diseases in Mumbai; Early Treatment Can Save Lives, Says Expert
Mumbai, July 08: With heavy monsoon showers and widespread waterlogging across Mumbai, healthcare experts at Apex Group of Hospitals have urged citizens to remain vigilant against leptospirosis and other water-borne diseases such as gastroenteritis, hepatitis A, typhoid, and diarrhoeal illnesses. Leptospirosis is a potentially life-threatening bacterial infection that spreads through water contaminated with the urine of infected rats and other...
READ MOREIIT Bhubaneswar Lends Technical Expertise for Safe Construction of Kendrapara Rath Yatra Chariot
Kendrapara, July 8 (UDN): In a unique blend of tradition and technology, the Indian Institute of Technology (IIT) Bhubaneswar is providing engineering support for the construction of the chariot for the upcoming Baladevjew Temple Rath Yatra at Ichapur in Odisha's Kendrapara district. Representational Image The annual Rath Yatra, scheduled to commence on July 16 , will witness the procession of...
READ MOREAdani Energy Project Opens New Chapter in Kenya-India Economic Partnership
New Delhi, July 8: The Adani Energy project has marked a significant step forward in strengthening economic cooperation between Kenya and India, paving the way for a new phase of collaboration in the energy sector. The project is expected to enhance infrastructure development, support Kenya’s energy requirements, and deepen bilateral ties between the two countries. The initiative reflects the growing...
READ MORERecent Post
- Government, corporates and global foundations join hands on PRAGATI to empower 20,000 agri-entrepreneurs
8 Jul 2026
- Genespire and SR-TIGET Show Durable Preclinical Efficacy of Liver-Directed Gene Therapy for Methylmalonic Acidemia
8 Jul 2026
- Poshan Tracker Achieves Milestone with 8.93 Crore Beneficiary Coverage
8 Jul 2026
- Robotic Surgery Successfully Removes Rare Tumour in 41-Year-Old Woman
8 Jul 2026
- MP Expands Digital Healthcare Reach Under Ayushman Bharat Mission
8 Jul 2026
- Monsoon Raises Risk of Leptospirosis and Water-Borne Diseases in Mumbai; Early Treatment Can Save Lives, Says Expert
8 Jul 2026
- IIT Bhubaneswar Lends Technical Expertise for Safe Construction of Kendrapara Rath Yatra Chariot
8 Jul 2026
- Adani Energy Project Opens New Chapter in Kenya-India Economic Partnership
8 Jul 2026
- Advancing Access to Blood Cancer Care in Hadapsar: Sahyadri Super Specialty Hospital Successfully Performs Autologous Stem Cell Transplant
8 Jul 2026
- Prime Volleyball League Receives FIVB Recognition
8 Jul 2026